iterm2 Clear all Sessions on Current Tab

On mac, save this as /Users/[username]/Library/Application Support/iTerm2/Scripts/AutoLaunch/clear_current_tab.py

#!/usr/bin/env python3

import asyncio
import iterm2
import time

async def main(connection):
    app = await iterm2.async_get_app(connection)
    @iterm2.RPC
    async def clear_current_tab():
        code = b'\x1b' + b']1337;ClearScrollback' + b'\x07'
        window = app.current_terminal_window
        tab = window.current_tab
        for session in tab.sessions:
            await session.async_inject(code)
    await clear_current_tab.async_register(connection)

iterm2.run_forever(main)

Now bind it to a keystroke in Prefs > Keys by selecting the action Invoke Script Function and giving it the invocation clear_current_tab().